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8 see this here well are you responding with your own information and current experience (e. This is also indicated by changes in the cumulative number of events and number at risk. For example, the probability of a member of the radiotherapy alone treatment group surviving (relapse-free) 45 days is the probability of surviving the first 36 days multiplied by the probability of then surviving the interval between 36 and 45 days. 7.

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If your cardholder is a child driver and you have registered the child driver yourself, log in to your IMDA with your ID and register him as a child driver. ininAboutHelpTermsPrivacyMachine Learning Engineer. In all, survivorship was higher among the spontaneously conceived children compared with those conceived through ART. bmj. This is in agreement with the previous study on the same cohort by Norrman et al. Reviewer #1:All comments have been addressedReviewer #2:All comments have been addressedReviewer #3:(No Response)**********2.

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Specifically, now that the authors clarified that “This study is a method paper with an application”, I think the paper should focus more on the models comparison (which is still just barely discussed):- The difference in interpretation between accelerated failure time and proportional hazards models is not discussed. If the event occurred in all individuals, many methods of analysis would be applicable. Similarly, the AIC and the BIC which are measures of information lost by each of the models were more favourable to the flexible models. Another example is that the AIC and the BIC are described well, but the paper is Look At This a sentence stating We used these criteria to assess which of the above described models was the optimal model. They are all based on a few central concepts that are important in find here time-to-event analysis, including censoring, survival functions, the hazard function, and cumulative hazards. ).

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However, KM had limited ability to handle measured confounders and was unable to describe the magnitude of difference between curves. Please clarify. For the new Oi and Ei, the test statistic for trend is compared with the 2 distribution with one degree of freedom (Collett, 1994). 041) higher among frozen-thawed transfer compared with those conceived spontaneously. WE AGREE. The current study established a higher risk of type-1 diabetes in the offspring of diabetic parents.

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The adjusted hazard of type-1 diabetes was 60% higher among children of both Swedish and other Nordic mothers than those of other European mothers while the hazard was about 76% higher among the children of both Swedish and other Nordic fathers than those of other European fathers. io to enhance the reproducibility of your results. WE AGREE, IT WAS PORIGINALLY CITED AS REF 18, WE HAVE NOW INSERTED STPM2 AND CITED IT ACCORDINGLY AS REF 19. Additionally, PLOS ONE offers an option for publishing peer-reviewed Lab Protocol articles, which describe protocols hosted on protocols. As PhD students, we found it difficult to access the research we needed, so we decided to create a new Open Access publisher that levels the playing field for scientists across the world.

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As it is, the CPH and FPSR are nearly identical proportional hazards models and no benefit of the FPSR can be made, other than also obtaining absolute rates and survival measures directly from the model without additional post-estimation as for CPH. Table 3: The birth cohort effect does not make sense. Ethical permission was given from the Regional Ethical Committee (es. Please ensure that your manuscript meets PLOS ONE’s style requirements, including those for file naming. The realm of health informatics lies at the heart of existence of subjects concerned with specific disease. The hazard is usually denoted by h(t) or λ(t) and is the probability that an individual who is under observation at a time t has an event at that time.

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, N) should perhaps be (i=1,2,,N). It generally provides the ratio between the predicted values to that of the actual one. , chances of getting heart attack, rather than group membership only. Given the subject area, is the hazard function presented in figure 3 with 6 degrees of freedom reasonable to the authors?YES, WE DIDNT PRODUCE ANY GRAPH IN FIGURE 3 WITH 6 DEGREES OF FREEDOM, RATHER WITH 3 DEGREES OF FREEDOM.